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Grey parrot with papilloma problems

We have a female African Grey approximately 30 years old and until recently been in good health. Our avian veterinarian found cloaca papillomas which were successfully removed with silver nitrate. Upon recheck they had returned. A more complex surgery was rejected as a treatment due to age and possibility of recurrence. We have tried Acyclovir with limited success. We are looking for any other reasonable treatment but have not found any. Any possible treatments that have a possibility of success that we should investigate would be greatly appreciated.

Overall, infectious papillomatous disease is comparatively quite rare in the grey parrot. My first recommendations would be to ask your attending veterinarian about the specific manner in which this diagnosis has been confirmed. Proper diagnosis requires biopsy with correlating histopathology. There is a facial papillomavirus infection reported in grey parrots, and there has been one grey parrot reported to be infected with Psittacid herpesvirus, but this bird did not have cloacal papillomas as has been seen in South American species of parrots. Acyclovir has been used in active herpesviral infections to help stop viral replication, but this drug has not been shown to have merit in the treatment of papillomatous disease associated with Psittacid herpesviral infections. Other considerations you may have to keep in mind here could include mechanically induced cloacal inflammation, bacterial cloacitis, or cloacal carcinoma. A carefully selected and diagnostic biopsy will get you quite far towards accurate diagnosis, with potentially an aerobic culture sample from the biopsy site. Once diagnosis is clarified, treatment should become much more straightforward.

About Brian Speer, DVM

Avian veterinarian Dr. Brian Speer was raised in a small town on California’s coast. He received his BS in Biology from California Polytechnic State University in 1978, and his DVM degree from the University of California at Davis in 1983.

An active member of the Association of Avian Veterinarians (AAV), Dr. Speer is a much sought after guest speaker and has presented at numerous conferences in the avicultural and zoological communities both within the United States and abroad. He is well published in the AAV annual proceedings, has served as guest editor for the journal Seminars in Avian and Exotic Pet Medicine, the Veterinary Clinics of North America, and authored chapters in several recent veterinary medical texts on pet bird, avicultural and ratite medical topics. In 1995 he co-authored the extensive avicultural reference, The Large Macaws, and helped to co-author Birds for Dummies in 1999.

Since 1989, Dr, Speer has run a “bird’s only” practice in the San Francisco Bay area and is the President and Director of The Medical Center for Birds. He is a consultant for The Veterinary Information Network (Avian Medical Boards) and the Maui Animal Rescue and Sanctuary. In 2003 he was the recipient of the Lafeber award for excellence in private practice of avian medicine and surgery and in 2006, was named Speaker of the Year for the North American Veterinary Conference.